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Not enough is known about the safety of jiaogulan during breast-feeding. “Auto-immune diseases” such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Jiaogulan might cause the immune system to become more active.

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If you have an auto-immune condition, it’s best to avoid using jiaogulan until more is known. Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells.

Bleeding disorders: Jiaogulan may slow blood clotting.

Takagi, J., Imada, T., Kikuchi, T., Saito, Y., and Inada, Y.

Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells.

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